findOutliers.func {aCGH} | R Documentation |

## Function to identify outlier clones

### Description

The function identified the clones that are outliers.

### Usage

findOutliers.func(thres = madGenome, factor = 4, statesres = states.bic)

### Arguments

`thres` |
Estimate of experimental variability, generally,
madGenome |

`factor` |
Factor indicating how many standard |

`statesres` |
The states output of the `hmm.run.func` |

### Details

The outliers are the clones that are dissimilar enough from the clones
assigned to the same state. Magnitude of the factor determines how
many MADs away from a median a value needs to be to be declared an
outlier. Outliers consitent over many samples may indicate
technological artificat with that clone or possibly copy number
polymorpism.

### Value

`outlier` |
Binary matrix with a row for each clone and column for
each sample. "1" indicates outlier, 0 otherwise. |

`pred.obs.out` |
Matrix with a row for each clone and column for
each sample. The entries are the median value for the state with
outliers exceluded for all clones but outliers. The value if the
observed value for the outliers. |

`pred.out` |
Matrix with a row for each clone and column for each
sample. The entries are the median value for the state |

### Author(s)

Jane Fridlyand

### References

Application of Hidden Markov Models to the analysis of the
array CGH data, Fridlyand et.al., *JMVA*, 2004

### See Also

`aCGH`

[Package

*aCGH* version 1.1.4

Index]