PBG {nlme} | R Documentation |

## Effect of Phenylbiguanide on Blood Pressure

### Description

The `PBG`

data frame has 60 rows and 5 columns.

### Format

This data frame contains the following columns:

- deltaBP
- a numeric vector
- dose
- a numeric vector
- Run
- an ordered factor with levels
`T5`

< `T4`

< `T3`

< `T2`

< `T1`

< `P5`

< `P3`

< `P2`

< `P4`

< `P1`

- Treatment
- a factor with levels
`MDL 72222`

`Placebo`

- Rabbit
- an ordered factor with levels
`5`

< `3`

< `2`

< `4`

< `1`

### Details

Data on an experiment to examine the effect of a antagonist MDL 72222
on the change in blood pressure experienced with increasing dosage of
phenylbiguanide are described in Ludbrook (1994) and analyzed
in Venables and Ripley (1999, section 8.8). Each of five rabbits was exposed to
increasing doses of phenylbiguanide after having either a placebo or
the HD5-antagonist MDL 72222 administered.

### Source

Pinheiro, J. C. and Bates, D. M. (2000), *Mixed-Effects Models in S
and S-PLUS*, Springer, New York. (Appendix A.21)

Venables, W. N. and Ripley, B. D. (1999) *Modern Applied
Statistics with S-PLUS (3rd ed)*, Springer, New York.

Ludbrook, J. (1994), Repeated measurements and multiple comparisons
in cardiovascular research, *Cardiovascular Research*,
**28**, 303-311.

[Package

*nlme* version 3.1-66

Index]